I love going to the the regional one-day user group conferences.
Usually held on a Saturday, they are a great way to learn about new technology, see old friends and make new ones. I have been known to drive up to 8 hours away to attend these events. Always well worth it.
I will be attending the West Michigan Day of .Net on May 10th in Grand Rapids, MI. See their web site for more information. This will be my second straight year attending this great event.